Clonality | polyclonal |
Host | Rabbit |
Specificity | Human |
Tested Application | ELISA, WB,IHC |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q08722 |
Gene ID | |
Calculated MW | 47-55 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus(By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Immunogen | CD47 molecule |
Synonyms | CD47, CD47 molecule, IAP, Leukocyte surface antigen CD47, MER6, OA3, Protein MER6 |
Recommended dilution | WB: 1:500-1:1000; IHC: 1:50-1:500 |
Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab01486(CD47 Antibody) at dilution of 1:200
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01486(CD47 antibody) at dilution of 1:500
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