Clonality | polyclonal |
Host | Rabbit |
Specificity | Human |
Tested Application | ELISA |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q99829 |
Gene ID | |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes(PubMed:14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner(PubMed:14674885). Exhibits calcium-dependent phospholipid binding properties(PubMed:9430674, PubMed:19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner(PubMed:23263657, PubMed:25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner(PubMed:12522145). May function in membrane trafficking(PubMed:9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit(PubMed:18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL(PubMed:18212740). |
Immunogen | copine I |
Synonyms | CPN1 |
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