Highlight | Pubmed/Publication |
Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse, Rat |
Tested Application | ELISA, IHC, WB, IP |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q13158 |
Gene ID | |
Calculated MW | 23 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Background | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
Immunogen | Fas(TNFRSF6)-associated via death domain |
Synonyms | MORT1 |
Immunohistochemistry of paraffin-embedded human lung cancer using FNab02941(FADD antibody) at dilution of 1:50
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HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab02941(FADD Antibody) at dilution of 1:300
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