anti- P53 antibodyСпецификацияHighlight | Pubmed/Publication | Clonality | polyclonal | Host | Rabbit | Specificity | Human, Rat | Tested Application | ELISA, WB, IHC, IF | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P04637 | Gene ID | | Calculated MW | 53 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) | Background | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). | Immunogen | tumor protein p53 | Synonyms | Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, P53, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53 | Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100 | Immunohistochemistry of paraffin-embedded human endometrial cancer using FNab06083(P53 antibody) at dilution of 1:100
| MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06083(P53 antibody) at dilution of 1:1000
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab06083 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- P53 antibody. Примечание: |
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