anti- Uromodulin antibodyСпецификацияClonality | polyclonal | Host | Rabbit | Specificity | Human, Mouse, Rat | Tested Application | ELISA, WB, IHC, IP | Delivery Time | 2 to 4 working days | Isotype | IgG | Form | liquid | Purification | Immunogen affinity purified | Purity | ≥95% as determined by SDS-PAGE | Uniprot ID | P07911 | Calculated MW | 12 kDa | Ссылка на страницу на сайте производителя | ссылка | Инструкция | PDF | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | Background | Uromodulin, also known as THP(Tamm-Horsfall glycoprotein), is the most abundant protein excreted in the urine under physiological conditions. Uromodulin is synthesized by kidney and localizes in cells lining the ascending limb of Henle and distal convoluted tubule. Uromodulin has been linked to water/electrolyte balance and to kidney innate immunity. Also, studies in knockout mice demonstrated that it has a protective role against urinary tract infections and renal stone formation. Mutations in the gene encoding uromodulin lead to rare autosomal dominant diseases, collectively referred to as uromodulin-associated kidney diseases.(PMID: 21654721) | Immunogen | uromodulin | Synonyms | ADMCKD2, FJHN, HNFJ, MCKD2, THGP, THP, UMOD, uromodulin | Recommended dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IP: 1:200-1:2000 | Immunohistochemistry of paraffin-embedded human kidney using FNab09294(UMOD antibody) at dilution of 1:50
| human heart tissue were subjected to SDS PAGE followed by western blot with FNab09294(UMOD antibody) at dilution of 1:400
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Информация для заказаОбласть использования: | Производство: | Fine Biotech | Метод: | Антитела | Объем: | 100µg | Кат. номер: | FNab09294 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: anti- Uromodulin antibody. Примечание: |
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