Антитела поликлональные кроличьи IgG к CEACAM1(H-136)CEACAM1 Antibody (H-136) is a rabbit polyclonal IgG
- CEACAM1 Antibody (H-136) is a rabbit polyclonal IgG provided at 200 µg/ml
- epitope corresponding to amino acids 391-526 mapping at the C-terminus of CEACAM1 of human origin
- recommended for detection CEACAM1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA
Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-lik C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue three-dimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression. Информация для заказаОбласть использования: | Производство: | Santa Cruz | Метод: | | Объем: | 200 мкг/мл | Кат. номер: | sc-25627 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Антитела поликлональные кроличьи IgG к CEACAM1(H-136) / CEACAM1 Antibody (H-136) is a rabbit polyclonal IgG. Примечание: SQ Category: Primary Antibodies, Species: human, Host Origin: human, Applications: WB, IP, IF, ELISA, UNSPSC: 12352203, datasheet |
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