Мышиные моноклональные антитела к GAPDHGAPDH (0411)
- GAPDH Antibody (0411) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against recombinant GAPDH of human origin
- recommended for detection of GAPDH of mouse, rat and human origin by WB, IP, IF and IHC(P)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. While GAPDH has long been recognized as playing an integral role in glycolysis, additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the b-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins. Информация для заказаОбласть использования: | Производство: | Santa Cruz | Метод: | Иммуногистохимия | Объем: | 200 мкг/мл | Кат. номер: | sc-47724 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Мышиные моноклональные антитела к GAPDH / GAPDH (0411). Примечание: Видоспецифичность: мышь, крыса, человек. Описание: мышиный моноклональный IgG1. Приложение: вестерн блоттинг, иммунопреципитация, иммунофлуоресценция. Доставка на голубом льду, Хранение при 4° C, Подробное описание (на английском языке). |
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