Epo Antibody (H-162) is a rabbit polyclonal IgG
- Epo Antibody (H-162) is a rabbit polyclonal IgG provided at 200 µg/ml
- epitope corresponding to amino acids 28-189 representing mature erythropoietin (Epo) of human origin
- recommended for detection of Epo of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See 26 citations for Epo Antibody (H-162)
Erythropoietin, or Epo, is the primary factor responsible for regulating erythropoiesis during steady-state conditions and in response to blood loss and hemorrhage in the adult organism. In addition, Epo has also been shown to play a role in primitive embryonic erythropoiesis. Epo is synthesized by the kidney and stimulates the proliferation and maturation of bone marrow erythroid precursor cells. Circulating Epo is a 165 amino acid glycoprotein. The Epo receptor, EpoR, is a glycoprotein expressed on megakaryocytes, erythroid progenitors and endothelial cells. Overexpression of Epo is associated with several pathophysiological conditions, such as polycythemias vera, which is caused by the Epo-independent growth of erythrocytic progenitors from abnormal stem cells. A deficiency in Epo expression has been associated with afflictions such as anemia of chronic disease (ACD), frequently found in rheumatoid arthritis (RA) patients.
Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-7956 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Epo Antibody (H-162) is a rabbit polyclonal IgG.
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
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