AF/LE Purified Anti-Human CD274/PD-L1 Monoclonal AntibodyСпецификация| Описание | CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells. | | Метод | Block, FA, FCM, IHC | | Хозяин | Mouse | | Специфичность | Human | | Концентрация | 0.2 mg/mL | | Коньюгат | None (Purified antibody,Azide Free/Low endotoxin) | | Буфер | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay. | | Клон | 29E.2A3 | | Gene_ID | 29126 | | Swissprot | Q9NZQ7 | | Isotype | Mouse IgG2b, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 1 мг | | Кат. номер: | DL21663F-1 m | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: AF/LE Purified Anti-Human CD274/PD-L1 Monoclonal Antibody.
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