AF/LE Purified Anti-Mouse CD22 Monoclonal AntibodyСпецификация| Описание | The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb. | | Метод | FCM,IP | | Хозяин | Mouse | | Специфичность | Mouse | | Концентрация | 0.2 mg/mL | | Коньюгат | None (Purified antibody,Azide Free/Low endotoxin) | | Буфер | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay. | | Клон | Cy34.1 | | Gene_ID | 12483 | | Swissprot | P35329 | | Isotype | Mouse IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 500 ?g | | Кат. номер: | DL20362F-500 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: AF/LE Purified Anti-Mouse CD22 Monoclonal Antibody.
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