AF/LE Purified Anti-Mouse CD54 Monoclonal AntibodyСпецификация| Описание | CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. | | Метод | FCM,IF | | Хозяин | Rat | | Специфичность | Mouse | | Концентрация | 0.2 mg/mL | | Коньюгат | None (Purified antibody,Azide Free/Low endotoxin) | | Буфер | 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay. | | Клон | YN1/1.7.4 | | Gene_ID | 15894 | | Swissprot | P13597 | | Isotype | Rat IgG2b, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 500 ?g | | Кат. номер: | DL20339F-500 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: AF/LE Purified Anti-Mouse CD54 Monoclonal Antibody.
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