Anti-Human CD197/CCR7 Monoclonal Antibody(AF488 Conjugated)Спецификация| Описание | CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. Product Details | | Метод | FCM | | Хозяин | Mouse | | Специфичность | Human | | Коньюгат | AF488 | | Буфер | PBS with 0.05% Proclin300, 1% BSA | | Клон | G043H7 | | Gene_ID | 1236 | | Swissprot | P32248 | | Isotype | Mouse IgG2a, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 50 tests | | Кат. номер: | DL21854F-50 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Anti-Human CD197/CCR7 Monoclonal Antibody(AF488 Conjugated).
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