Anti-Human CD49d Monoclonal Antibody(FITC Conjugated)Спецификация| Описание | CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells. | | Метод | FCM | | Хозяин | Mouse | | Специфичность | Human | | Коньюгат | FITC | | Буфер | PBS with 0.05% Proclin300, 1% BSA | | Клон | BU49 | | Gene_ID | 3676 | | Swissprot | P13612 | | Isotype | Mouse IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 200 tests | | Кат. номер: | DL20594F-200 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Anti-Human CD49d Monoclonal Antibody(FITC Conjugated).
Примечание: |
|
