Anti-Human IL-17A Monoclonal Antibody(APC Conjugated)Спецификация| Описание | IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively. | | Метод | ICFCM | | Хозяин | Mouse | | Специфичность | Human | | Коньюгат | APC | | Буфер | PBS with 0.05% Proclin300, 1% BSA | | Клон | BL168 | | Gene_ID | 3605 | | Swissprot | Q16552 | | Isotype | Mouse IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 50 tests | | Кат. номер: | DL21925F-50 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Anti-Human IL-17A Monoclonal Antibody(APC Conjugated).
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