Anti-Human Notch3 Monoclonal Antibody(APC Conjugated)Спецификация| Описание | The Notch receptors are highly conserved from invertebrates to mammals. While Notch 1 and Notch 2 exhibit the highest structural similarity among the four mammalian Notch receptors. Notch 3 has a number of structural and functional differences. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. Notch 3 is primarily expressed in adult arterial smooth muscle cells. Notch3 gene mutation can cause CADASIL, a hereditary early stroke syndrome. | | Метод | FCM | | Хозяин | Mouse | | Специфичность | Human | | Коньюгат | APC | | Буфер | PBS with 0.05% Proclin300, 1% BSA | | Клон | MHN3-21 | | Gene_ID | 4854 | | Swissprot | Q9UM47 | | Isotype | Mouse IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 50 tests | | Кат. номер: | DL21927F-50 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Anti-Human Notch3 Monoclonal Antibody(APC Conjugated).
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