Anti-Mouse CD22 Monoclonal Antibody(PerCP/Cyanine5.5 Conjugated)СпецификацияОписание | The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb. | Метод | FCM | Хозяин | Mouse | Специфичность | Mouse | Коньюгат | PerCP/Cyanine5.5 | Буфер | PBS with 0.05% Proclin300, 1% BSA | Клон | Cy34.1 | Gene_ID | 12483 | Swissprot | P35329 | Isotype | Mouse IgG1, κ | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | Описание на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | DLDEVELOP | Метод: | Антитела | Объем: | 20 Tests | Кат. номер: | DL20371F-20 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Anti-Mouse CD22 Monoclonal Antibody(PerCP/Cyanine5.5 Conjugated). Примечание: |
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