Anti-Mouse CD45R/B220 Monoclonal Antibody(APC Conjugated)Спецификация| Описание | CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-2CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is eessed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.40 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 is one of the best negative selection markers for characterizing and/or isolating human mesenchymal stem cells from bone marrow and other sources. s. | | Метод | FCM | | Хозяин | Rat | | Специфичность | Mouse | | Концентрация | 0.2 mg/mL | | Коньюгат | APC | | Буфер | PBS with 0.05% Proclin300, 1% BSA | | Клон | RA3.3A 1/6.1 | | Gene_ID | 19264,5788 | | Swissprot | P06800,P08575 | | Isotype | Rat IgM | | Хранение | Store at 2~8℃. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 200 ?g | | Кат. номер: | DL21375F-200 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Anti-Mouse CD45R/B220 Monoclonal Antibody(APC Conjugated).
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