Anti-Mouse CD54 Monoclonal Antibody(AF647 Conjugated)СпецификацияОписание | CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. | Метод | FCM | Хозяин | Rat | Специфичность | Mouse | Коньюгат | AF647 | Буфер | PBS with 0.05% Proclin300, 1% BSA | Клон | YN1/1.7.4 | Gene_ID | 15894 | Swissprot | P13597 | Isotype | Rat IgG2b, κ | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | Описание на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | DLDEVELOP | Метод: | Антитела | Объем: | 50 tests | Кат. номер: | DL20351F-50 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Anti-Mouse CD54 Monoclonal Antibody(AF647 Conjugated). Примечание: |
|