Anti-Mouse IL-17A Monoclonal Antibody(PE Conjugated)Спецификация| Описание | IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course. | | Метод | ICFCM | | Хозяин | Rat | | Специфичность | Mouse | | Коньюгат | PE | | Буфер | PBS with 0.05% Proclin300, 1% BSA | | Клон | TC11-18H10.1 | | Gene_ID | 16171 | | Swissprot | Q62386 | | Isotype | Rat IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 20 Tests | | Кат. номер: | DL22160F-20 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Anti-Mouse IL-17A Monoclonal Antibody(PE Conjugated).
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