Purified Anti-Human CD22 Monoclonal AntibodyСпецификацияОписание | CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial. | Метод | FCM | Хозяин | Mouse | Специфичность | Human | Концентрация | 0.2 mg/mL | Коньюгат | Unconjugated | Буфер | PBS with 0.05% Proclin300 | Клон | BU59 | Gene_ID | 933 | Swissprot | P20273 | Isotype | Mouse IgG1, κ | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | Описание на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | DLDEVELOP | Метод: | Антитела | Объем: | 25 ?g | Кат. номер: | DL20664F-25 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Purified Anti-Human CD22 Monoclonal Antibody. Примечание: |
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