Purified Anti-Human CD279/PD-1 Monoclonal AntibodyСпецификация| Описание | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. | | Метод | FCM, IHC | | Хозяин | Mouse | | Специфичность | Human | | Концентрация | 0.2 mg/mL | | Коньюгат | Unconjugated | | Буфер | PBS with 0.05% Proclin300 | | Клон | J110 | | Gene_ID | 3683 | | Swissprot | P20701 | | Isotype | Mouse IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 100 ?g | | Кат. номер: | DL22250F-100 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Purified Anti-Human CD279/PD-1 Monoclonal Antibody.
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