Purified Anti-Human CD40 Monoclonal AntibodyСпецификацияОписание | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. | Метод | FCM | Хозяин | Mouse | Специфичность | Human | Концентрация | 0.2 mg/mL | Коньюгат | Unconjugated | Буфер | PBS with 0.05% Proclin300 | Клон | 3A8 | Gene_ID | 958 | Swissprot | P25942 | Isotype | Mouse IgG2a, κ | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | Описание на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | DLDEVELOP | Метод: | Антитела | Объем: | 100 ?g | Кат. номер: | DL20556F-100 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Purified Anti-Human CD40 Monoclonal Antibody. Примечание: |
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