Purified Anti-Human CD45 Monoclonal AntibodyСпецификация| Описание | CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. | | Метод | FCM | | Хозяин | Mouse | | Специфичность | Human | | Концентрация | 0.2 mg/mL | | Коньюгат | Unconjugated | | Буфер | PBS with 0.05% Proclin300 | | Клон | 9.4 | | Gene_ID | 5788 | | Swissprot | P08575 | | Isotype | Mouse IgG2a, κ | | Хранение | Store at 2~8℃. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 25 ?g | | Кат. номер: | DL20580F-25 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Purified Anti-Human CD45 Monoclonal Antibody.
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