Purified Anti-Human CD47 Monoclonal AntibodyСпецификация| Описание | CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes. | | Метод | FCM | | Хозяин | Mouse | | Специфичность | Human | | Концентрация | 0.2 mg/mL | | Коньюгат | Unconjugated | | Буфер | PBS with 0.05% Proclin300 | | Клон | CC2C6D4 | | Gene_ID | 961 | | Swissprot | Q08722 | | Isotype | Mouse IgG1, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 100 ?g | | Кат. номер: | DL20772F-100 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Purified Anti-Human CD47 Monoclonal Antibody.
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