Purified Anti-Mouse CD274/PD-L1 Monoclonal AntibodyСпецификация| Описание | CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production. | | Метод | FCM,IHC,IF | | Хозяин | Rat | | Специфичность | Mouse | | Концентрация | 0.2 mg/mL | | Коньюгат | Unconjugated | | Буфер | PBS with 0.05% Proclin300 | | Клон | 10F.9G2 | | Gene_ID | 60533 | | Swissprot | Q9EP73 | | Isotype | Rat IgG2b, κ | | Хранение | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | | Описание на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | DLDEVELOP | | Метод: | Антитела | | Объем: | 100 ?g | | Кат. номер: | DL21655F-100 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Purified Anti-Mouse CD274/PD-L1 Monoclonal Antibody.
Примечание: |
|
