Мышиные моноклональные антитела к MyoD (5.8A) MyoD (5.8A) (мышечно-специфический фактор транскрипции)
- MyoD Antibody (5.8A) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against recombinant MyoD of mouse origin with an epitope mapping to amino acids 180-189
- recommended for detection of MyoD of mouse, rat and human origin by WB, IP, IF and IHC(P); non cross-reactive with other MyoD family members
- TransCruz reagent for Gel Supershift and ChIP applications, sc-32758 X, 200 µg/0.1 ml
- See 4 citations for MyoDAntibody (5.8A)
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes MyoD, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either MyoD or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. MyoD transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. MyoD-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-32758 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Мышиные моноклональные антитела к MyoD (5.8A) / MyoD (5.8A) (мышечно-специфический фактор транскрипции).
Примечание: Видоспецифичность: мышь, крыса, человек.
Описание: мышиный моноклональный IgG1.
Приложение: вестерн блоттинг, иммунопреципитация, иммунофлуоресценция, иммуногистохимия.
Доставка на голубом льду, хранение при 4°C.
Подробное описание (на английском языке). |
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