Объем | 50 мкг |
Категория | Drug Target |
Подраздел | Immune Checkpoint |
Области исследований | Cancer |
Uniprot NO# | Q07011 |
Наименование гена | TNFRSF9 |
Специфичность | Homo sapiens (Human) |
Источник | Mammalian cell |
Регион экспрессии | 24-186aa |
Последовательность | LQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHSPQ |
Описание белка | Extracellular Domain |
Информация о TAG | C-terminal 6xHis-FC-tagged |
Мол. вес | 44 kDa |
Примечание | специальная цена до 30.06.2019! |
Биологическая активность | The ED50 as determined by its ability to bind Human TNFSF9 in functional ELISA is less than 50 ug/ml. |
Очистка | Greater than 95% as determined by SDS-PAGE. |
Эндотоксин | Less than 1.0 EU/µg as determined by LAL method. |
Буфер хранения | Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4 |
Альтернативное имя / Синоним | CD137;ILA;TNFRSF9;4-1BB ligand receptor;CDw137;T-cell antigen 4-1BB homolog;T-cell antigen ILA |
Актуальность | Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. |
Функция | Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation. |
Субклеточное расположение | Membrane, Single-pass type I membrane protein |
Тканевая специфичность | Expressed on the surface of activated T-cells. |
HGNC Database Link | ссылка |
UniGene Database Link | ссылка |
KEGG Database Link | ссылка |
STRING Database Link | ссылка |
OMIM Database Link | ссылка |
Ссылка на страницу на сайте производителя | ссылка |
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