CREB1 (Ab-142) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CREB-1, CREB1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P16220 | | Иммуноген | Peptide sequence around aa.140~144 (D-L-S-S-D) derived from Human CREB. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,IHC:1:50-1:100 | | Примечание | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.<br/><br/>Chrystelle V. Garat, et al. (2006) Mol. Cell. Biol , 26: 4934 - 4948.<br/>Lilah Rothem,et al. (2004) Mol. Pharmacol , 66: 1536 - 1543.<br/>Darren R. Tyson, et,al. (2002) Endocrinology, 143: 674.<br/>Kyung-Woo Park, et al. (2003) Arterioscler. Thromb. Vasc. Biol , 23: 1364.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB(Ab-142) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: CREB1 (Ab-142) Antibody.