GSK3A/GSK3B (Ab-279/216) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Factor A, GSK-3 alpha/beta, kinase GSK3-alpha/beta | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P49840/P49841 | Иммуноген | Peptide sequence around aa.277~281/214~218 (V-S-Y-I-C) derived from Human GSK3 / . | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | <p>Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. <br /><br />Chin PC, et al. Brain Res Mol Brain Res 2005 Jun 13, 137(1-2): 193-201 <br />Takahashi-Yanaga F, et al. Biochem Biophys Res Commun 2004 Apr 02, 316(2): 411-415 <br />Fan G, et al. J Biol Chem 2003 Dec 26, 278(52): 52432-52436 <br />Liao X, et al. Mol Cancer Ther 2003 Nov, 2(11): 1215-1222</p> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cardiovascular,Cell biology,Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HL60, HT29 and 293 cells using GSK3-alpha;/β(Ab-279/216) Antibody.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкл | Кат. номер: | CSB-PA255909 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: GSK3A/GSK3B (Ab-279/216) Antibody. Примечание: дополнительная информация (на английском языке). |
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