Объем | 100 мкл |
Синонимы | I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK2, IkBKB, NFKBIKB |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O14920 |
Иммуноген | Peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-b. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IF,WB:1:500-1:1000, IF:1:100-1:200 |
Примечание | Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.<br/><br/>Chen RA, et al. PLoS Pathog. 2008 Feb 8,4(2):e22<br/>Yen CJ,et al. Cancer Res. 2008 Apr 15,68(8):2632-40<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Cancer,Cardiovascular,Cell biology,Immunology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from MDA cells using IKK-b(Ab-199) Antibody.
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Immunofluorescence staining of methanol-fixed Hela cells using IKK-b(Ab-199) Antibody.
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