MCL1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | TM, EAT, MCL1L, BCL2L3, mcl1/EAT | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q07820 | Иммуноген | Peptide sequence around aa.148~152(N-N-T-S-T) derived from Human MCL1. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<br/><br/>Bingle C.D., Craig R.W., Swales B.M., Singleton V., Zhou P., Whyte M.K.B.J. Biol. Chem. 275:22136-22146(2000)<br/>Zhang D., Li F., Weidner D., Mnjoyan Z.H., Fujise K.J. Biol. Chem. 277:37430-37438(2002)<br/>Leu J.I.-J., Dumont P., Hafey M., Murphy M.E., George D.L.Nat. Cell Biol. 6:443-450(2004) | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cancer,Cell biology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Raji, JK, HL-60 cells using MCL1 Antibody.
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