BAX AntibodyСпецификация| Объем | 50 мкл | | Синонимы | BCL2-associated X protein | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q07812 | | Иммуноген | Fusion protein of human BAX | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | | Примечание | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Cell biology,Metabolism | | Ссылка на страницу на сайте производителя | ссылка | Gel: 8+12%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: Human brain malignant glioma tissue, MCF7 cells, Raji cells, Lovo cells, 293T cells, Primary antibody: CSB-PA221042(BAX Antibody) at dilution 1/426, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 7 seconds
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Наименование: BAX Antibody.