CYCS AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CYCS, CYC, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P99999 | | Иммуноген | Synthesized peptide derived from human Cytochrome c. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.<br/><br/>R. Pullerits, Rheumatology, Jan 2005, 44: 32 - 39.<br/>Bogdan Polevoda, J. Biol. Chem., Jun 2000, 275: 20508<br/>Larry A. Allen, J. Biol. Chem., Jan 1995, 270: 110.<br/>Akemi MATSUSHIMA, J. Biochem. (Tokyo), Jan 1986, 100: 543 - 551.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COS7 cells, using Cytochrome c antibody.
 | Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue, using Cytochrome c antibody.
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Наименование: CYCS Antibody.