CREB1 (Ab-133) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CREB-1, CREB1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P16220 | | Иммуноген | Peptide sequence around aa. 131~135 (R-P-S-Y-R) derived from Human CREB. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.<br/><br/>Xing J, et al. (1998) Mol Cell Biol 18(4): 1946-55.<br/>Tan Y, et al.( 1996) EMBO J, 15(17): 4629-42.<br/>Hao, M. et al. (1996) J. Biol. Chem. 271, 29380-29385.<br/>Mayo LD, et al. (2001) Biol Chem, 276(27): 25184-9.<br/>Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-5934.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293, HT29 and Hela cells using CREB(Ab-133) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CREB(Ab-133) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: CREB1 (Ab-133) Antibody.