MFN2 Antibody, HRP conjugated

Спецификация

Объем	50 мкг
Синонимы	Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2), MFN2, CPRP1 KIAA0214
Клональность	Polyclonal Antibody
Организм	Human
uniprot	O95140
Иммуноген	Recombinant Human Mitofusin-2 protein (61-158AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	HRP
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Mitofusin-2
Области исследований	Neuroscience, Cancer, Cell biology, Tags & Cell Markers, Metabolism, Signal transduction
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Информация для заказа

Область использования: Антитела MFN2 Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA013756LB01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: MFN2 Antibody, HRP conjugated. Примечание: дополнительная информация (на английском языке).