Объем | 100 мкг |
Синонимы | Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa), PMAIP1, NOXA |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q13794 |
Иммуноген | Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, IF, Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Phorbol-12-myristate-13-acetate-induced protein 1 |
Области исследований | Cancer, Cell biology, Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA018229LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018229LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA018229LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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