MCL1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | EAT/MCL-1 protein, Induced myeloid leukemia cell differentiation protein Mcl-1, Myeloid cell leukemia sequence 1., | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q07820 | Иммуноген | Synthesized peptide derived from human MCL1. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<br/><br/>Alfredo De Biasio, J. Biol. Chem., Jun 2007, 10.1074.<br/>Potchanapond Graidist, J. Biol. Chem., Sep 2004, 279: 40868 - 40875. <br/>Kenichi Fujise, J. Biol. Chem., Dec 2000, 275: 39458. <br/>Di Zhang, J. Biol. Chem., Sep 2002, 277: 37430 - 37438. <br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cancer,Cell biology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MCL1 antibody.
| Western blot analysis of extracts from HuvEc cells, using MCL1 antibody.
| Western blot analysis of extracts from HuvEc cells (Lane 2), JK cells (Lane 3) and cos-7 cells (Lane 4), using MCL1 antiobdy. The lane on the left is treated with synthesized peptide.
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