Объем | 100 мкл |
Синонимы | Tumor necrosis factor ligand superfamily member 10, TNF-related apoptosis-inducing ligand, Protein TRAIL, Apo-2 ligand, Apo-2L |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P50591 |
Иммуноген | Synthesized peptide derived from internal of human CD253. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
Примечание | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.<br/><br/>Wiley S.R., Immunity 3:673-682(1995).<br/>Pitti R.M., J. Biol. Chem. 271:12687-12690(1996).<br/>Hymowitz S.G., Mol. Cell 4:563-571(1999).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cardiovascular,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells and HUVEC cells, using CD253 antibody.
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Immunofluorescence analysis of A549 cells, using CD253 antibody.
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