Clonality | polyclonal |
Host | Rabbit |
Specificity | Human, Mouse |
Tested Application | ELISA, WB, IHC, IF |
Delivery Time | 2 to 4 working days |
Isotype | IgG |
Form | liquid |
Purification | Immunogen affinity purified |
Purity | ≥95% as determined by SDS-PAGE |
Uniprot ID | Q99933 |
Gene ID | |
Calculated MW | 43 kDa |
Ссылка на страницу на сайте производителя | ссылка |
Инструкция | PDF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
Background | The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti- apoptotic effects of BCL2 and represents a link between growth factor receptors and anti- apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. |
Immunogen | BCL2-associated athanogene |
Synonyms | HAP |
Recommended dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100 |
Immunohistochemistry of paraffin-embedded human esophagus using FNab00786(BAG1 antibody) at dilution of 1:50
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab00786(BAG1 antibody) at dilution of 1:1000
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