Recombinant Alpha-enolase protein
Relevance: Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production. Ref.3 Ref.18 Ref.20 Ref.21 Ref.22 MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: 1] "Molecular cloning and nucleotide sequence of a full-length cDNA for human alpha enolase." Giallongo A., Feo S., Moore R., Croce C.M., Showe L.C. Proc. Natl. Acad. Sci. U.S.A. 83:6741-6745(1986) [PubMed: 3529090] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA-ENOLASE). [2] "Structure of the human gene for alpha-enolase." Giallongo A., Oliva D., Cali L., Barba G., Barbieri G., Feo S. Eur. J. Biochem. 190:567-573(1990) [PubMed: 2373081] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM ALPHA-ENOLASE). Tissue: T-cell. [3] "Cloning and characterization of a human c-myc promoter-binding protein." Ray R., Miller D.M. Mol. Cell. Biol. 11:2154-2161(1991) [PubMed: 2005901] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM MBP-1), FUNCTION. Tissue: Cervix carcinoma.
Alias: 2-phospho-D-glycerate hydro-lyase,C-myc promoter-binding protein,Enolase 1,MBP-1,MPB-1,Non-neural enolase,NNE,Phosphopyruvate hydratase,Plasminogen-binding protein.
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