Recombinant human Beta-2-microglobulin protein
Relevance: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
Product Info: His tagged
Source: E.coli derived
Purity: 95%
Image:
Tested applications: ELISA, Western blot
Storage Buffer: PBS buffer
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence: QRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDR
Referrences: [1] "The beta-2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon." Rosa F., Berissi H., Weissenbach J., Maroteaux L., Fellous M., Revel M. EMBO J. 2:239-243(1983) [2] "Isolation of a granulocyte inhibitory protein from uraemic patients with homology of beta 2-microglobulin." Haag-Weber M., Mai B., Hoerl W.H. Nephrol. Dial. Transplant. 9:382-388(1994)
Alias: .
Информация для заказа
Область использования: | Производство: | Cusabio |
Метод: | |
Объем: | 500 мкг |
Кат. номер: | CSB-RP057874h |
Цена (с НДС 20%): | по запросу | В корзину |
Наименование: Recombinant human Beta-2-microglobulin protein. Примечание: дополнительная информация (на английском языке). |