Recombinant human Cathepsin D protein
Relevance: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: 6M guanidine hydrochloride, 20mM Tris
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Cloning and sequence analysis of cDNA for human cathepsin D." Faust P.L., Kornfeld S., Chirgwin J.M. Proc. Natl. Acad. Sci. U.S.A. 82:4910-4914(1985) [PubMed: 3927292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] "Oestrogen regulates cathepsin D mRNA levels in oestrogen responsive human breast cancer cells." Westley B.R., May F.E.B. Nucleic Acids Res. 15:3773-3786(1987) [PubMed: 3588310] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [3] "Molecular organization of the human cathepsin D gene." Redecker B., Heckendorf B., Grosch H.W., Mersmann G., Hasilik A. DNA Cell Biol. 10:423-431(1991) [PubMed: 2069717] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Alias: .
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