Recombinant human C-C motif chemokine 14 protein

Relevance: Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
Product Info: GST tagged
Source: E.coli derived
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "HCC-1, a novel chemokine from human plasma." Schulz-Knappe P., Maegert H.-J., Dewald B., Meyer M., Cetin Y., Kubbies M., Tomeczkowski J., Kirchhoff K., Raida M., Adermann K., Kist A., Reinecke M., Sillard R., Pardigol A., Uguccioni M., Baggiolini M., Forssmann W.-G. J. Exp. Med. 183:295-299(1996) [PubMed: 8551235] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM HCC-1), PROTEIN SEQUENCE OF 20-93. Tissue: Bone marrow. [2] "HCC-2, a human chemokine: gene structure, expression pattern, and biological activity." Pardigol A., Forssmann U., Zucht H.-D., Loetscher P., Schulz-Knappe P., Baggiolini M., Forssmann W.-G., Maegert H.-J. Proc. Natl. Acad. Sci. U.S.A. 95:6308-6313(1998) [PubMed: 9600961] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS HCC-1 AND HCC-3), TISSUE SPECIFICITY. Tissue: Liver. [3] "Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, LEC, and RANTES." Nomiyama H., Fukuda S., Iio M., Tanase S., Miura R., Yoshie O. J. Interferon Cytokine Res. 19:227-234(1999) [PubMed: 10213461] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Alias: Chemokine CC-1/CC-3,HCC-1/HCC-3.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	50 мкг
	Кат. номер:	CSB-RP058944h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human C-C motif chemokine 14 protein. Примечание: дополнительная информация (на английском языке).