Recombinant human Cystatin-C protein
Relevance: As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity. Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: ELISA, Western blot, PETIA
Storage Buffer: PBS Buffer
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20." Saitoh E., Sabatini L.M., Eddy R.L., Shows T.B., Azen E.A., Isemura S., Sanada K. Biochem. Biophys. Res. Commun. 162:1324-1331(1989) [2] "Stroke in Icelandic patients with hereditary amyloid angiopathy is related to a mutation in the cystatin C gene, an inhibitor of cysteine proteases." Levy E., Lopez-Otin C., Ghiso J., Geltner D., Frangione B. J. Exp. Med. 169:1771-1778(1989)
Alias: .
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