Recombinant human Diamine acetyltransferase 1 protein
Relevance: Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Isolation and characterization of a cDNA clone that codes for human spermidine/spermine N1-acetyltransferase." Casero R.A. Jr., Celano P., Ervin S.J., Applegren N.B., Wiest L., Pegg A.E. J. Biol. Chem. 266:810-814(1991) [PubMed: 1985966] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [2] "Characterization of a full-length cDNA which codes for the human spermidine/spermine N1-acetyltransferase." Xiao L., Celano P., Mank A.R., Pegg A.E., Casero R.A. Jr. Biochem. Biophys. Res. Commun. 179:407-415(1991) [PubMed: 1652956] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Lung. [3] "Structure of the human spermidine/spermine N1-acetyltransferase gene (exon/intron gene organization and localization to Xp22.1)." Xiao L., Celano P., Mank A.R., Griffin C., Wang J.E., Casero R.A. Jr. Biochem. Biophys. Res. Commun. 187:1493-1502(1992) [PubMed: 1417826] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Alias: Polyamine N-acetyltransferase 1,Putrescine acetyltransferase,Spermidine/spermine N(1)-acetyltransferase 1,SSAT,SSAT-1.
Информация для заказа
Область использования: | Производство: | Cusabio |
Метод: | |
Объем: | 500 мкг |
Кат. номер: | CSB-RP027544h |
Цена (с НДС 20%): | по запросу | В корзину |
Наименование: Recombinant human Diamine acetyltransferase 1 protein. Примечание: дополнительная информация (на английском языке). |