Recombinant human Fibronectin protein

Relevance: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Ref.36 Ref.38 Ref.42 Ref.50 Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling. Ref.36 Ref.38 Ref.42 Ref.50
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0,200 mM Imidazole
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Phenotypic and genetic alterations in mammary stroma: implications for tumour progression." Schor S.L., Schor A.M. Breast Cancer Res. 3:373-379(2001) [PubMed: 11737888] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), VARIANTS PRO-817 AND ILE-2170. [2] "Vector-capping: a simple method for preparing a high-quality full-length cDNA library." Kato S., Ohtoko K., Ohtake H., Kimura T. DNA Res. 12:53-62(2005) [PubMed: 16106752] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 14), VARIANTS PRO-817 AND ILE-2170. Tissue: Retinal pigment epithelium. [3] Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 14), VARIANTS LEU-15; PRO-817 AND ILE-2170. Tissue: Aortic endothelium.
Alias: Cold-insoluble globulin,CIG.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	500 мкг
	Кат. номер:	CSB-RP131874h(A5)
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Fibronectin protein. Примечание: дополнительная информация (на английском языке).