Recombinant human HCLS1-associated protein X-1 protein

Relevance: Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools.
Product Info: GST-tagged
Source: E.coli derived
Purity: 95%
Image:
Tested applications: SDS-PAGE, ELISA, Western blot.
Storage Buffer: PBS buffer,20mM GSH.
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence: SLFDLFRGFFGFPGPRSHRDPFFGGMTRDEDDDEEEEEEGGSWGRGNPRFHSPQHPPEEFGFGFSFSPGGGIRFHDNFGFDDLVRDFNSIFSDMGAWTLPSHPPELPGPESETPGERLREGQTLRDSMLKYPDSHQPRIFGGVLESDARSESPQPAPDWGSQRPFHRFDDVWPMDPHPRTREDNDLDSQVSQEGLGPVLQPQPKSYFKSISVTKITKPDGIVEERRTVVDSEGRTETTVTRHEADSSPR
Referrences: [1] "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." Suzuki Y., Demoliere C., Kitamura D., Takeshita H., Deuschle U., Watanabe T. J. Immunol. 158:2736-2744(1997) [PubMed: 9058808] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH HCLS1, TISSUE SPECIFICITY. Tissue: Cervix adenocarcinoma. [2] "Existence of multiple isoforms of HS1-associated protein X-1 in murine and human tissues." Lees D.M., Hart I.R., Marshall J.F. J. Mol. Biol. 379:645-655(2008) [PubMed: 18472110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4; 5 AND 6). [3] Trebinska A., Grzybowska E.A. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 3 AND 4). Tissue: Lung.
Alias: HS1-associating protein X-1,HAX-1,HS1-binding protein 1,HSP1BP-1.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	50 мкг
	Кат. номер:	CSB-RP035144h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human HCLS1-associated protein X-1 protein. Примечание: дополнительная информация (на английском языке).