Recombinant human Metalloproteinase inhibitor 3 protein

Relevance: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Product Info:
Source:
Purity: 90%
Image:
Tested applications: SDS-PAGE, ELISA
Storage Buffer: PBS buffer, 20mM GSH
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family." Uria J.A., Ferrando A.A., Velasco G., Freije J.M., Lopez-Otin C. Cancer Res. 54:2091-2094(1994) [PubMed: 8174111] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Mammary carcinoma. [2] "Cloning and characterization of human tissue inhibitor of metalloproteinases-3." Wilde C.G., Hawkins P.R., Coleman R.T., Levine W.B., Delegeane A.M., Okamoto P.M., Ito L.Y., Scott R.W., Seilhamer J.J. DNA Cell Biol. 13:711-718(1994) [PubMed: 7772252] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [3] "Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family." Silbiger S.M., Jacobsen V.L., Cupples R.L., Koski R.A. Gene 141:293-297(1994) [PubMed: 8163205] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Kidney.
Alias: Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	200 мкг
	Кат. номер:	CSB-RP117444h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Metalloproteinase inhibitor 3 protein. Примечание: дополнительная информация (на английском языке).