Recombinant human NT-proBNP protein
Relevance: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Product Info:
Source:
Purity: 95%
Image:
Tested applications: ELISA, Western blot
Storage Buffer: 20mM Tris-Hcl, 0.5M NaCl, 10% glycerin, PH 8.0; 200 mM Imidazole
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [2] "Isolation and identification of human brain natriuretic peptides in cardiac atrium." Hino J., Tateyaa H., Minamino N., Kangawa K., Matsuo H. Biochem. Biophys. Res. Commun. 167:693-700(1990)
Alias: Gamma-brain natriuretic peptide.
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