Recombinant human Nucleoside diphosphate kinase A protein

Relevance: Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
Product Info:
Source:
Purity: 95%
Image:
Tested applications: SDS-PAGE, ELISA, Western blot
Storage Buffer: 6M guanidine hydrochloride,20mM Tris
Storage: Store at -20?, for extended storage, conserve at -20? or -80?.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week.
AA sequence:
Referrences: [1] "Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development." Rosengard A.M., Krutzsch H.C., Shearn A., Biggs J.R., Barker E., Margulies I.M.K., King C.R., Liotta L.A., Steeg P.S. Nature 342:177-180(1989) [PubMed: 2509941] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). [2] "Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme." Gilles A.-M., Presecan E., Vonica A., Lascu I. J. Biol. Chem. 266:8784-8789(1991) [PubMed: 1851158] [Abstract] Cited for: PROTEIN SEQUENCE (ISOFORM 1), SUBUNIT, ACTIVE SITE. [3] "Mutation in the nm23 gene is associated with metastasis in colorectal cancer." Wang L., Patel U., Ghosh L., Chen H.C., Banerjee S. Cancer Res. 53:717-720(1993) [PubMed: 7916650] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Alias: NDK A,NDP kinase A,Granzyme A-activated DNase,GAAD,Metastasis inhibition factor nm23,Tumor metastatic process-associated protein,nm23-H1.

Информация для заказа

Область использования: Рекомбинантные белки Cusabio	Производство:	Cusabio
	Метод:
	Объем:	500 мкг
	Кат. номер:	CSB-RP027754h
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Recombinant human Nucleoside diphosphate kinase A protein. Примечание: дополнительная информация (на английском языке).